A DISRUPTED FOXP3 TRANSCRIPTIONAL SIGNATURE UNDERPINS SYSTEMIC REGULATORY T CELL INSUFFICIENCY IN EARLY PREGNANCY FAILURE

A disrupted FOXP3 transcriptional signature underpins systemic regulatory T cell insufficiency in early pregnancy failure

Summary: Regulatory T (Treg) cell defects are implicated in disorders of embryo implantation and placental development, but the origins of Treg cell dysfunction are unknown.Here, we comprehensively analyzed the phenotypes and transcriptional profile of peripheral blood Treg cells in individuals with early pregnancy failure (EPF).Compared to 3 Piece

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A NB-IoT access scheme based on Beta distribution

As one of the emerging technologies of low-power wide-area Internet of things, narrow band Internet of things (NB-IoT) faces the pressure and challenge of massive connections of terminals.Aiming at practical application scenarios, a preamble allocation scheme based on Beta distribution was proposed.In this scheme, the energy consumption of each tim

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The Complexity of Skeletal Transverse Dimension: From Diagnosis, Management, and Treatment Strategies to the Application of Collaborative Cross (CC) Mouse Model

This study investigates the significance of skeletal transverse dimension (STD) in orthodontic therapy and its impact on occlusal relationships.The primary goal is to enhance understanding and promote the integration of transverse skeletal diagnostics into routine orthodontic assessments.To achieve this aim, the study employs a comprehensive approa

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